Wearing‐off scales in Parkinson's disease: Critique and recommendations
Identifieur interne : 000219 ( Main/Corpus ); précédent : 000218; suivant : 000220Wearing‐off scales in Parkinson's disease: Critique and recommendations
Auteurs : Angelo Antonini ; Pablo Martinez-Martin ; Ray K. Chaudhuri ; Marcelo Merello ; Robert Hauser ; Regina Katzenschlager ; Per Odin ; Mark Stacy ; Fabrizio Stocchi ; Werner Poewe ; Oliver Rascol ; Cristina Sampaio ; Anette Schrag ; Glenn T. Stebbins ; Christopher G. GoetzSource :
- Movement Disorders [ 0885-3185 ] ; 2011-10.
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Abstract
Wearing‐off occurs in the majority of patients with Parkinson's disease after a few years of dopaminergic therapy. Because a variety of scales have been used to estimate wearing‐off, the Movement Disorder Society commissioned a task force to assess their clinimetric properties. A systematic review was conducted to identify wearing‐off scales that have either been validated or used in Parkinson's patients. A scale was designated “Recommended” if it had been used in clinical studies beyond the group that developed it, if it had been specifically used in Parkinson's disease reports, and if clinimetric studies had established that it is valid, reliable, and sensitive. “Suggested” scales met 2 of the above criteria, and those meeting 1 were “Listed.” We identified 3 diagnostic and 4 severity rating scales for wearing‐off quantification. Two questionnaires met the criteria to be Recommended for diagnostic screening (questionnaires for 19 and 9 items), and 1 was Suggested (questionnaire for 32 items). Only the patient diaries were Recommended to assess wearing‐off severity, with the caveat of relatively limited knowledge of validity. Among the other severity assessment tools, the Unified Parkinson Disease Rating Scale version 3 and the version revised from the Movement Disorders Society were classified as Suggested, whereas the Treatment Response Scale was Listed. © 2011 Movement Disorder Society
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DOI: 10.1002/mds.23875
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National Center for Epidemiology and CIBERNED, Carlos III Institute of Health, Madrid, Spain</mods:affiliation></affiliation></author><author><name sortKey="Chaudhuri, Ray K" sort="Chaudhuri, Ray K" uniqKey="Chaudhuri R" first="Ray K." last="Chaudhuri">Ray K. Chaudhuri</name><affiliation><mods:affiliation>National Parkinson Foundation Centre of Excellence, Kings College and Institute of Psychiatry, London, United Kingdom</mods:affiliation></affiliation></author><author><name sortKey="Merello, Marcelo" sort="Merello, Marcelo" uniqKey="Merello M" first="Marcelo" last="Merello">Marcelo Merello</name><affiliation><mods:affiliation>Movement Disorders Section. FLENI. Buenos Aires, Argentina</mods:affiliation></affiliation></author><author><name sortKey="Hauser, Robert" sort="Hauser, Robert" uniqKey="Hauser R" first="Robert" last="Hauser">Robert Hauser</name><affiliation><mods:affiliation>Department of Neurology, University of South Florida, Tampa, Florida, USA</mods:affiliation></affiliation></author><author><name sortKey="Katzenschlager, Regina" sort="Katzenschlager, Regina" uniqKey="Katzenschlager R" first="Regina" last="Katzenschlager">Regina Katzenschlager</name><affiliation><mods:affiliation>Department of Neurology, Danube Hospital/SMZ‐Ost, Vienna, Austria</mods:affiliation></affiliation></author><author><name sortKey="Odin, Per" sort="Odin, Per" uniqKey="Odin P" first="Per" last="Odin">Per Odin</name><affiliation><mods:affiliation>Department of Neurology, Central Hospital, Bremerhaven, Germany</mods:affiliation></affiliation></author><author><name sortKey="Stacy, Mark" sort="Stacy, Mark" uniqKey="Stacy M" first="Mark" last="Stacy">Mark Stacy</name><affiliation><mods:affiliation>Duke University Medical Center, Durham, North Carolina, USA</mods:affiliation></affiliation></author><author><name sortKey="Stocchi, Fabrizio" sort="Stocchi, Fabrizio" uniqKey="Stocchi F" first="Fabrizio" last="Stocchi">Fabrizio Stocchi</name><affiliation><mods:affiliation>Institute of Neurology, IRCCS “San Raffaele,” Rome, Italy</mods:affiliation></affiliation></author><author><name sortKey="Poewe, Werner" sort="Poewe, Werner" uniqKey="Poewe W" first="Werner" last="Poewe">Werner Poewe</name><affiliation><mods:affiliation>Department of Neurology, University Hospital, Innsbruck, Austria</mods:affiliation></affiliation></author><author><name sortKey="Rascol, Oliver" sort="Rascol, Oliver" uniqKey="Rascol O" first="Oliver" last="Rascol">Oliver Rascol</name><affiliation><mods:affiliation>Laboratoire de Pharmacologie Medicale et Clinique, Toulouse, France</mods:affiliation></affiliation></author><author><name sortKey="Sampaio, Cristina" sort="Sampaio, Cristina" uniqKey="Sampaio C" first="Cristina" last="Sampaio">Cristina Sampaio</name><affiliation><mods:affiliation>Laboratory of Clinical Pharmacology and Therapeutics, Lisbon School of Medicine, Lisbon, Portugal</mods:affiliation></affiliation></author><author><name sortKey="Schrag, Anette" sort="Schrag, Anette" uniqKey="Schrag A" first="Anette" last="Schrag">Anette Schrag</name><affiliation><mods:affiliation>Department of Clinical Neurosciences, Institute of Neurology, University College London, London, United Kingdom</mods:affiliation></affiliation></author><author><name sortKey="Stebbins, Glenn T" sort="Stebbins, Glenn T" uniqKey="Stebbins G" first="Glenn T." last="Stebbins">Glenn T. Stebbins</name><affiliation><mods:affiliation>Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia, USA</mods:affiliation></affiliation></author><author><name sortKey="Goetz, Christopher G" sort="Goetz, Christopher G" uniqKey="Goetz C" first="Christopher G." last="Goetz">Christopher G. Goetz</name><affiliation><mods:affiliation>Department of Neurological Services, Rush University Medical Center, Chicago, Illinois, USA</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2011-10">2011-10</date><biblScope unit="volume">26</biblScope><biblScope unit="issue">12</biblScope><biblScope unit="page" from="2169">2169</biblScope><biblScope unit="page" to="2175">2175</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">6DFE24D10C1F444D89FCA80D0BC179386E8C815E</idno><idno type="DOI">10.1002/mds.23875</idno><idno type="ArticleID">MDS23875</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Parkinson's disease</term><term>clinimetrics</term><term>psychometrics</term><term>rating scales</term><term>reliability</term><term>validity</term><term>wearing‐off</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Wearing‐off occurs in the majority of patients with Parkinson's disease after a few years of dopaminergic therapy. Because a variety of scales have been used to estimate wearing‐off, the Movement Disorder Society commissioned a task force to assess their clinimetric properties. A systematic review was conducted to identify wearing‐off scales that have either been validated or used in Parkinson's patients. A scale was designated “Recommended” if it had been used in clinical studies beyond the group that developed it, if it had been specifically used in Parkinson's disease reports, and if clinimetric studies had established that it is valid, reliable, and sensitive. “Suggested” scales met 2 of the above criteria, and those meeting 1 were “Listed.” We identified 3 diagnostic and 4 severity rating scales for wearing‐off quantification. Two questionnaires met the criteria to be Recommended for diagnostic screening (questionnaires for 19 and 9 items), and 1 was Suggested (questionnaire for 32 items). Only the patient diaries were Recommended to assess wearing‐off severity, with the caveat of relatively limited knowledge of validity. Among the other severity assessment tools, the Unified Parkinson Disease Rating Scale version 3 and the version revised from the Movement Disorders Society were classified as Suggested, whereas the Treatment Response Scale was Listed. © 2011 Movement Disorder Society</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Angelo Antonini MD, PhD</name><affiliations><json:string>Department for Parkinson's Disease and Movement Disorders, IRCCS “San Camillo,” Venice, Italy</json:string></affiliations></json:item><json:item><name>Pablo Martinez‐Martin MD</name><affiliations><json:string>Area of Applied Epidemiology. National Center for Epidemiology and CIBERNED, Carlos III Institute of Health, Madrid, Spain</json:string></affiliations></json:item><json:item><name>Ray K. Chaudhuri MD</name><affiliations><json:string>National Parkinson Foundation Centre of Excellence, Kings College and Institute of Psychiatry, London, United Kingdom</json:string></affiliations></json:item><json:item><name>Marcelo Merello MD, PhD</name><affiliations><json:string>Movement Disorders Section. FLENI. Buenos Aires, Argentina</json:string></affiliations></json:item><json:item><name>Robert Hauser MD</name><affiliations><json:string>Department of Neurology, University of South Florida, Tampa, Florida, USA</json:string></affiliations></json:item><json:item><name>Regina Katzenschlager MD</name><affiliations><json:string>Department of Neurology, Danube Hospital/SMZ‐Ost, Vienna, Austria</json:string></affiliations></json:item><json:item><name>Per Odin MD</name><affiliations><json:string>Department of Neurology, Central Hospital, Bremerhaven, Germany</json:string></affiliations></json:item><json:item><name>Mark Stacy MD</name><affiliations><json:string>Duke University Medical Center, Durham, North Carolina, USA</json:string></affiliations></json:item><json:item><name>Fabrizio Stocchi</name><affiliations><json:string>Institute of Neurology, IRCCS “San Raffaele,” Rome, Italy</json:string></affiliations></json:item><json:item><name>Werner Poewe MD</name><affiliations><json:string>Department of Neurology, University Hospital, Innsbruck, Austria</json:string></affiliations></json:item><json:item><name>Oliver Rascol MD</name><affiliations><json:string>Laboratoire de Pharmacologie Medicale et Clinique, Toulouse, France</json:string></affiliations></json:item><json:item><name>Cristina Sampaio MD</name><affiliations><json:string>Laboratory of Clinical Pharmacology and Therapeutics, Lisbon School of Medicine, Lisbon, Portugal</json:string></affiliations></json:item><json:item><name>Anette Schrag MD, PhD</name><affiliations><json:string>Department of Clinical Neurosciences, Institute of Neurology, University College London, London, United Kingdom</json:string></affiliations></json:item><json:item><name>Glenn T. Stebbins PhD</name><affiliations><json:string>Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia, USA</json:string></affiliations></json:item><json:item><name>Christopher G. Goetz MD</name><affiliations><json:string>Department of Neurological Services, Rush University Medical Center, Chicago, Illinois, USA</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Parkinson's disease</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>wearing‐off</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>clinimetrics</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>psychometrics</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>rating scales</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>validity</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>reliability</value></json:item></subject><articleId><json:string>MDS23875</json:string></articleId><language><json:string>eng</json:string></language><abstract>Wearing‐off occurs in the majority of patients with Parkinson's disease after a few years of dopaminergic therapy. Because a variety of scales have been used to estimate wearing‐off, the Movement Disorder Society commissioned a task force to assess their clinimetric properties. A systematic review was conducted to identify wearing‐off scales that have either been validated or used in Parkinson's patients. A scale was designated “Recommended” if it had been used in clinical studies beyond the group that developed it, if it had been specifically used in Parkinson's disease reports, and if clinimetric studies had established that it is valid, reliable, and sensitive. “Suggested” scales met 2 of the above criteria, and those meeting 1 were “Listed.” We identified 3 diagnostic and 4 severity rating scales for wearing‐off quantification. Two questionnaires met the criteria to be Recommended for diagnostic screening (questionnaires for 19 and 9 items), and 1 was Suggested (questionnaire for 32 items). Only the patient diaries were Recommended to assess wearing‐off severity, with the caveat of relatively limited knowledge of validity. Among the other severity assessment tools, the Unified Parkinson Disease Rating Scale version 3 and the version revised from the Movement Disorders Society were classified as Suggested, whereas the Treatment Response Scale was Listed. © 2011 Movement Disorder Society</abstract><qualityIndicators><score>7.404</score><pdfVersion>1.4</pdfVersion><pdfPageSize>612 x 810 pts</pdfPageSize><refBibsNative>true</refBibsNative><keywordCount>7</keywordCount><abstractCharCount>1412</abstractCharCount><pdfWordCount>4372</pdfWordCount><pdfCharCount>28262</pdfCharCount><pdfPageCount>7</pdfPageCount><abstractWordCount>211</abstractWordCount></qualityIndicators><title>Wearing‐off scales in Parkinson's disease: Critique and recommendations</title><genre><json:string>review-article</json:string></genre><host><volume>26</volume><publisherId><json:string>MDS</json:string></publisherId><pages><total>7</total><last>2175</last><first>2169</first></pages><issn><json:string>0885-3185</json:string></issn><issue>12</issue><subject><json:item><value>Review</value></json:item></subject><genre><json:string>Journal</json:string></genre><language><json:string>unknown</json:string></language><eissn><json:string>1531-8257</json:string></eissn><title>Movement Disorders</title><doi><json:string>10.1002/(ISSN)1531-8257</json:string></doi></host><publicationDate>2011</publicationDate><copyrightDate>2011</copyrightDate><doi><json:string>10.1002/mds.23875</json:string></doi><id>6DFE24D10C1F444D89FCA80D0BC179386E8C815E</id><fulltext><json:item><original>true</original><mimetype>application/pdf</mimetype><extension>pdf</extension><uri>https://api.istex.fr/document/6DFE24D10C1F444D89FCA80D0BC179386E8C815E/fulltext/pdf</uri></json:item><json:item><original>false</original><mimetype>application/zip</mimetype><extension>zip</extension><uri>https://api.istex.fr/document/6DFE24D10C1F444D89FCA80D0BC179386E8C815E/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/6DFE24D10C1F444D89FCA80D0BC179386E8C815E/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Wearing‐off scales in Parkinson's disease: Critique and recommendations</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><availability><p>WILEY</p></availability><date>2011</date></publicationStmt><notesStmt><note type="content">*Relevant conflicts of interest/financial disclosures: Nothing to report.</note><note type="content">*Full financial disclosures and author roles may be found in the online version of this article.</note></notesStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Wearing‐off scales in Parkinson's disease: Critique and recommendations</title><author><persName><forename type="first">Angelo</forename><surname>Antonini</surname></persName><roleName type="degree">MD, PhD</roleName><note type="correspondence"><p>Correspondence: Parkinson Department, IRCCS “San Camillo,” Via Alberoni 70, Venice, Italy</p></note><affiliation>Department for Parkinson's Disease and Movement Disorders, IRCCS “San Camillo,” Venice, Italy</affiliation></author><author><persName><forename type="first">Pablo</forename><surname>Martinez‐Martin</surname></persName><roleName type="degree">MD</roleName><affiliation>Area of Applied Epidemiology. National Center for Epidemiology and CIBERNED, Carlos III Institute of Health, Madrid, Spain</affiliation></author><author><persName><forename type="first">Ray K.</forename><surname>Chaudhuri</surname></persName><roleName type="degree">MD</roleName><affiliation>National Parkinson Foundation Centre of Excellence, Kings College and Institute of Psychiatry, London, United Kingdom</affiliation></author><author><persName><forename type="first">Marcelo</forename><surname>Merello</surname></persName><roleName type="degree">MD, PhD</roleName><affiliation>Movement Disorders Section. FLENI. Buenos Aires, Argentina</affiliation></author><author><persName><forename type="first">Robert</forename><surname>Hauser</surname></persName><roleName type="degree">MD</roleName><affiliation>Department of Neurology, University of South Florida, Tampa, Florida, USA</affiliation></author><author><persName><forename type="first">Regina</forename><surname>Katzenschlager</surname></persName><roleName type="degree">MD</roleName><affiliation>Department of Neurology, Danube Hospital/SMZ‐Ost, Vienna, Austria</affiliation></author><author><persName><forename type="first">Per</forename><surname>Odin</surname></persName><roleName type="degree">MD</roleName><affiliation>Department of Neurology, Central Hospital, Bremerhaven, Germany</affiliation></author><author><persName><forename type="first">Mark</forename><surname>Stacy</surname></persName><roleName type="degree">MD</roleName><affiliation>Duke University Medical Center, Durham, North Carolina, USA</affiliation></author><author><persName><forename type="first">Fabrizio</forename><surname>Stocchi</surname></persName><affiliation>Institute of Neurology, IRCCS “San Raffaele,” Rome, Italy</affiliation></author><author><persName><forename type="first">Werner</forename><surname>Poewe</surname></persName><roleName type="degree">MD</roleName><affiliation>Department of Neurology, University Hospital, Innsbruck, Austria</affiliation></author><author><persName><forename type="first">Oliver</forename><surname>Rascol</surname></persName><roleName type="degree">MD</roleName><affiliation>Laboratoire de Pharmacologie Medicale et Clinique, Toulouse, France</affiliation></author><author><persName><forename type="first">Cristina</forename><surname>Sampaio</surname></persName><roleName type="degree">MD</roleName><affiliation>Laboratory of Clinical Pharmacology and Therapeutics, Lisbon School of Medicine, Lisbon, Portugal</affiliation></author><author><persName><forename type="first">Anette</forename><surname>Schrag</surname></persName><roleName type="degree">MD, PhD</roleName><affiliation>Department of Clinical Neurosciences, Institute of Neurology, University College London, London, United Kingdom</affiliation></author><author><persName><forename type="first">Glenn T.</forename><surname>Stebbins</surname></persName><roleName type="degree">PhD</roleName><affiliation>Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia, USA</affiliation></author><author><persName><forename type="first">Christopher G.</forename><surname>Goetz</surname></persName><roleName type="degree">MD</roleName><affiliation>Department of Neurological Services, Rush University Medical Center, Chicago, Illinois, USA</affiliation></author></analytic><monogr><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="pISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><idno type="DOI">10.1002/(ISSN)1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2011-10"></date><biblScope unit="volume">26</biblScope><biblScope unit="issue">12</biblScope><biblScope unit="page" from="2169">2169</biblScope><biblScope unit="page" to="2175">2175</biblScope></imprint></monogr><idno type="istex">6DFE24D10C1F444D89FCA80D0BC179386E8C815E</idno><idno type="DOI">10.1002/mds.23875</idno><idno type="ArticleID">MDS23875</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2011</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>Wearing‐off occurs in the majority of patients with Parkinson's disease after a few years of dopaminergic therapy. Because a variety of scales have been used to estimate wearing‐off, the Movement Disorder Society commissioned a task force to assess their clinimetric properties. A systematic review was conducted to identify wearing‐off scales that have either been validated or used in Parkinson's patients. A scale was designated “Recommended” if it had been used in clinical studies beyond the group that developed it, if it had been specifically used in Parkinson's disease reports, and if clinimetric studies had established that it is valid, reliable, and sensitive. “Suggested” scales met 2 of the above criteria, and those meeting 1 were “Listed.” We identified 3 diagnostic and 4 severity rating scales for wearing‐off quantification. Two questionnaires met the criteria to be Recommended for diagnostic screening (questionnaires for 19 and 9 items), and 1 was Suggested (questionnaire for 32 items). Only the patient diaries were Recommended to assess wearing‐off severity, with the caveat of relatively limited knowledge of validity. Among the other severity assessment tools, the Unified Parkinson Disease Rating Scale version 3 and the version revised from the Movement Disorders Society were classified as Suggested, whereas the Treatment Response Scale was Listed. © 2011 Movement Disorder Society</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>Parkinson's disease</term></item><item><term>wearing‐off</term></item><item><term>clinimetrics</term></item><item><term>psychometrics</term></item><item><term>rating scales</term></item><item><term>validity</term></item><item><term>reliability</term></item></list></keywords></textClass><textClass><keywords scheme="Journal Subject"><list><head>article category</head><item><term>Review</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2011-03-14">Received</change><change when="2011-05-16">Registration</change><change when="2011-10">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/6DFE24D10C1F444D89FCA80D0BC179386E8C815E/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Wiley Subscription Services, Inc., A Wiley Company</publisherName><publisherLoc>Hoboken</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1531-8257</doi><issn type="print">0885-3185</issn><issn type="electronic">1531-8257</issn><idGroup><id type="product" value="MDS"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="MOVEMENT DISORDERS">Movement Disorders</title><title type="short">Mov. Disord.</title></titleGroup></publicationMeta><publicationMeta level="part" position="120"><doi origin="wiley" registered="yes">10.1002/mds.v26.12</doi><numberingGroup><numbering type="journalVolume" number="26">26</numbering><numbering type="journalIssue">12</numbering></numberingGroup><coverDate startDate="2011-10">October 2011</coverDate></publicationMeta><publicationMeta level="unit" type="reviewArticle" position="50" status="forIssue"><doi origin="wiley" registered="yes">10.1002/mds.23875</doi><idGroup><id type="unit" value="MDS23875"></id></idGroup><countGroup><count type="pageTotal" number="7"></count></countGroup><titleGroup><title type="articleCategory">Review</title><title type="tocHeading1">Reviews</title></titleGroup><copyright ownership="thirdParty">Copyright © 2011 Movement Disorder Society</copyright><eventGroup><event type="manuscriptReceived" date="2011-03-14"></event><event type="manuscriptAccepted" date="2011-05-16"></event><event type="xmlConverted" 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type="referenceTotal" number="39"></count><count type="wordTotal" number="5500"></count></countGroup><titleGroup><title type="main" xml:lang="en">Wearing‐off scales in Parkinson's disease: Critique and recommendations<link href="#fn1"></link><link href="#fn2"></link></title><title type="short" xml:lang="en">Scales to Assess Wearing‐Off in PD</title></titleGroup><creators><creator xml:id="au1" creatorRole="author" affiliationRef="#af1" corresponding="yes"><personName><givenNames>Angelo</givenNames><familyName>Antonini</familyName><degrees>MD, PhD</degrees></personName><contactDetails><email>angelo3000@yahoo.com</email></contactDetails></creator><creator xml:id="au2" creatorRole="author" affiliationRef="#af2"><personName><givenNames>Pablo</givenNames><familyName>Martinez‐Martin</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au3" creatorRole="author" affiliationRef="#af3"><personName><givenNames>Ray K.</givenNames><familyName>Chaudhuri</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au4" creatorRole="author" affiliationRef="#af4"><personName><givenNames>Marcelo</givenNames><familyName>Merello</familyName><degrees>MD, PhD</degrees></personName></creator><creator xml:id="au5" creatorRole="author" affiliationRef="#af5"><personName><givenNames>Robert</givenNames><familyName>Hauser</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au6" creatorRole="author" affiliationRef="#af6"><personName><givenNames>Regina</givenNames><familyName>Katzenschlager</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au7" creatorRole="author" affiliationRef="#af7"><personName><givenNames>Per</givenNames><familyName>Odin</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au8" creatorRole="author" 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affiliationRef="#af13"><personName><givenNames>Anette</givenNames><familyName>Schrag</familyName><degrees>MD, PhD</degrees></personName></creator><creator xml:id="au14" creatorRole="author" affiliationRef="#af14"><personName><givenNames>Glenn T.</givenNames><familyName>Stebbins</familyName><degrees>PhD</degrees></personName></creator><creator xml:id="au15" creatorRole="author" affiliationRef="#af15"><personName><givenNames>Christopher G.</givenNames><familyName>Goetz</familyName><degrees>MD</degrees></personName></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="IT" type="organization"><unparsedAffiliation>Department for Parkinson's Disease and Movement Disorders, IRCCS “San Camillo,” Venice, Italy</unparsedAffiliation></affiliation><affiliation xml:id="af2" countryCode="ES" type="organization"><unparsedAffiliation>Area of Applied Epidemiology. National Center for Epidemiology and CIBERNED, Carlos III Institute of Health, Madrid, Spain</unparsedAffiliation></affiliation><affiliation xml:id="af3" countryCode="GB" type="organization"><unparsedAffiliation>National Parkinson Foundation Centre of Excellence, Kings College and Institute of Psychiatry, London, United Kingdom</unparsedAffiliation></affiliation><affiliation xml:id="af4" countryCode="AR" type="organization"><unparsedAffiliation>Movement Disorders Section. FLENI. Buenos Aires, Argentina</unparsedAffiliation></affiliation><affiliation xml:id="af5" countryCode="US" type="organization"><unparsedAffiliation>Department of Neurology, University of South Florida, Tampa, Florida, USA</unparsedAffiliation></affiliation><affiliation xml:id="af6" countryCode="AT" type="organization"><unparsedAffiliation>Department of Neurology, Danube Hospital/SMZ‐Ost, Vienna, Austria</unparsedAffiliation></affiliation><affiliation xml:id="af7" countryCode="DE" type="organization"><unparsedAffiliation>Department of Neurology, Central Hospital, Bremerhaven, Germany</unparsedAffiliation></affiliation><affiliation xml:id="af8" countryCode="US" type="organization"><unparsedAffiliation>Duke University Medical Center, Durham, North Carolina, USA</unparsedAffiliation></affiliation><affiliation xml:id="af9" countryCode="IT" type="organization"><unparsedAffiliation>Institute of Neurology, IRCCS “San Raffaele,” Rome, Italy</unparsedAffiliation></affiliation><affiliation xml:id="af10" countryCode="AT" type="organization"><unparsedAffiliation>Department of Neurology, University Hospital, Innsbruck, Austria</unparsedAffiliation></affiliation><affiliation xml:id="af11" countryCode="FR" type="organization"><unparsedAffiliation>Laboratoire de Pharmacologie Medicale et Clinique, Toulouse, France</unparsedAffiliation></affiliation><affiliation xml:id="af12" countryCode="PT" type="organization"><unparsedAffiliation>Laboratory of Clinical Pharmacology and Therapeutics, Lisbon School of Medicine, Lisbon, Portugal</unparsedAffiliation></affiliation><affiliation xml:id="af13" countryCode="GB" type="organization"><unparsedAffiliation>Department of Clinical Neurosciences, Institute of Neurology, University College London, London, United Kingdom</unparsedAffiliation></affiliation><affiliation xml:id="af14" countryCode="US" type="organization"><unparsedAffiliation>Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia, USA</unparsedAffiliation></affiliation><affiliation xml:id="af15" countryCode="US" type="organization"><unparsedAffiliation>Department of Neurological Services, Rush University Medical Center, Chicago, Illinois, USA</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en" type="author"><keyword xml:id="kwd1">Parkinson's disease</keyword><keyword xml:id="kwd2">wearing‐off</keyword><keyword xml:id="kwd3">clinimetrics</keyword><keyword xml:id="kwd4">psychometrics</keyword><keyword xml:id="kwd5">rating scales</keyword><keyword xml:id="kwd6">validity</keyword><keyword xml:id="kwd7">reliability</keyword></keywordGroup><supportingInformation><p> Additional Supporting Information may be found in the online version of this article. </p><supportingInfoItem><mediaResource alt="supporting information" href="urn-x:wiley:08853185:media:mds23875:MDS_23875_sm_suppinfo"></mediaResource><caption>Supporting Information</caption></supportingInfoItem></supportingInformation><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>Wearing‐off occurs in the majority of patients with Parkinson's disease after a few years of dopaminergic therapy. Because a variety of scales have been used to estimate wearing‐off, the Movement Disorder Society commissioned a task force to assess their clinimetric properties. A systematic review was conducted to identify wearing‐off scales that have either been validated or used in Parkinson's patients. A scale was designated “Recommended” if it had been used in clinical studies beyond the group that developed it, if it had been specifically used in Parkinson's disease reports, and if clinimetric studies had established that it is valid, reliable, and sensitive. “Suggested” scales met 2 of the above criteria, and those meeting 1 were “Listed.” We identified 3 diagnostic and 4 severity rating scales for wearing‐off quantification. Two questionnaires met the criteria to be Recommended for diagnostic screening (questionnaires for 19 and 9 items), and 1 was Suggested (questionnaire for 32 items). Only the patient diaries were Recommended to assess wearing‐off severity, with the caveat of relatively limited knowledge of validity. Among the other severity assessment tools, the Unified Parkinson Disease Rating Scale version 3 and the version revised from the Movement Disorders Society were classified as Suggested, whereas the Treatment Response Scale was Listed. © 2011 Movement Disorder Society</p></abstract></abstractGroup></contentMeta><noteGroup><note xml:id="fn1"><p><b>Relevant conflicts of interest/financial disclosures:</b> Nothing to report.</p></note><note xml:id="fn2"><p>Full financial disclosures and author roles may be found in the online version of this article.</p></note></noteGroup></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Wearing‐off scales in Parkinson's disease: Critique and recommendations</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Scales to Assess Wearing‐Off in PD</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Wearing‐off scales in Parkinson's disease: Critique and recommendations</title></titleInfo><name type="personal"><namePart type="given">Angelo</namePart><namePart type="family">Antonini</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>Department for Parkinson's Disease and Movement Disorders, IRCCS “San Camillo,” Venice, Italy</affiliation><description>Correspondence: Parkinson Department, IRCCS “San Camillo,” Via Alberoni 70, Venice, Italy</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Pablo</namePart><namePart type="family">Martinez‐Martin</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Area of Applied Epidemiology. National Center for Epidemiology and CIBERNED, Carlos III Institute of Health, Madrid, Spain</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Ray K.</namePart><namePart type="family">Chaudhuri</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>National Parkinson Foundation Centre of Excellence, Kings College and Institute of Psychiatry, London, United Kingdom</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Marcelo</namePart><namePart type="family">Merello</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>Movement Disorders Section. FLENI. Buenos Aires, Argentina</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Robert</namePart><namePart type="family">Hauser</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, University of South Florida, Tampa, Florida, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Regina</namePart><namePart type="family">Katzenschlager</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Danube Hospital/SMZ‐Ost, Vienna, Austria</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Per</namePart><namePart type="family">Odin</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Central Hospital, Bremerhaven, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Mark</namePart><namePart type="family">Stacy</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Duke University Medical Center, Durham, North Carolina, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Fabrizio</namePart><namePart type="family">Stocchi</namePart><affiliation>Institute of Neurology, IRCCS “San Raffaele,” Rome, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Werner</namePart><namePart type="family">Poewe</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, University Hospital, Innsbruck, Austria</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Oliver</namePart><namePart type="family">Rascol</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Laboratoire de Pharmacologie Medicale et Clinique, Toulouse, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Cristina</namePart><namePart type="family">Sampaio</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Laboratory of Clinical Pharmacology and Therapeutics, Lisbon School of Medicine, Lisbon, Portugal</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Anette</namePart><namePart type="family">Schrag</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>Department of Clinical Neurosciences, Institute of Neurology, University College London, London, United Kingdom</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Glenn T.</namePart><namePart type="family">Stebbins</namePart><namePart type="termsOfAddress">PhD</namePart><affiliation>Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Christopher G.</namePart><namePart type="family">Goetz</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurological Services, Rush University Medical Center, Chicago, Illinois, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="review-article" displayLabel="reviewArticle"></genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2011-10</dateIssued><dateCaptured encoding="w3cdtf">2011-03-14</dateCaptured><dateValid encoding="w3cdtf">2011-05-16</dateValid><copyrightDate encoding="w3cdtf">2011</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="tables">2</extent><extent unit="references">39</extent><extent unit="words">5500</extent></physicalDescription><abstract lang="en">Wearing‐off occurs in the majority of patients with Parkinson's disease after a few years of dopaminergic therapy. Because a variety of scales have been used to estimate wearing‐off, the Movement Disorder Society commissioned a task force to assess their clinimetric properties. A systematic review was conducted to identify wearing‐off scales that have either been validated or used in Parkinson's patients. A scale was designated “Recommended” if it had been used in clinical studies beyond the group that developed it, if it had been specifically used in Parkinson's disease reports, and if clinimetric studies had established that it is valid, reliable, and sensitive. “Suggested” scales met 2 of the above criteria, and those meeting 1 were “Listed.” We identified 3 diagnostic and 4 severity rating scales for wearing‐off quantification. Two questionnaires met the criteria to be Recommended for diagnostic screening (questionnaires for 19 and 9 items), and 1 was Suggested (questionnaire for 32 items). Only the patient diaries were Recommended to assess wearing‐off severity, with the caveat of relatively limited knowledge of validity. Among the other severity assessment tools, the Unified Parkinson Disease Rating Scale version 3 and the version revised from the Movement Disorders Society were classified as Suggested, whereas the Treatment Response Scale was Listed. © 2011 Movement Disorder Society</abstract><note type="content">*Relevant conflicts of interest/financial disclosures: Nothing to report.</note><note type="content">*Full financial disclosures and author roles may be found in the online version of this article.</note><subject lang="en"><genre>Keywords</genre><topic>Parkinson's disease</topic><topic>wearing‐off</topic><topic>clinimetrics</topic><topic>psychometrics</topic><topic>rating scales</topic><topic>validity</topic><topic>reliability</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><genre type="Journal">journal</genre><note type="content"> Additional Supporting Information may be found in the online version of this article.Supporting Info Item: Supporting Information - </note><subject><genre>article category</genre><topic>Review</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>26</number></detail><detail type="issue"><caption>no.</caption><number>12</number></detail><extent unit="pages"><start>2169</start><end>2175</end><total>7</total></extent></part></relatedItem><identifier type="istex">6DFE24D10C1F444D89FCA80D0BC179386E8C815E</identifier><identifier type="DOI">10.1002/mds.23875</identifier><identifier type="ArticleID">MDS23875</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2011 Movement Disorder Society</accessCondition><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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